Our research group (AG Translational Immunometabolism) is interested in the interplay between metabolism and
immunity.
The number of people with obesity is continuously rising but new weight loss drugs have revolutionised the treatment over the last years. Obesity leads to a severe course of infections, but the underlying mechanisms are not fully understood. The PhD project will investigate the impact of obesity, weight loss and novel metabolic therapies on antiviral T-cell immunity.
The successful candidate will utilize high-dimensional flow
cytometry and metabolic assays with the goal to identify
mechanisms that impair antiviral immunity in obese individuals and define metabolic pathways that could be targeted to improve infection outcomes.
We are a young and dynamic research group funded by the
Else Kröner-Fresenius-Stiftung and the University of Cologne. We offer team spirit and a supportive environment with close supervision by the PI. We have strong local and international collaborations, and our group is part of the Translational Research Unit – Infectious Diseases (TRU-ID) within the Division of Infectious Diseases. The TRU-ID conducts research aimed at improving our immunological understanding of infectious diseases with the goal to develop innovative therapies for bacterial, viral and fungal infections.