You will independently plan and execute a translational PhD project with direct clinical relevance. Your responsibilities include:
- Detection, analysis, and functional characterization of HIV-1 envelope sequences
- In vitro and in vivo testing of HIV-1 antibody sensitivity
- Analysis of HIV-1 sequence diversity and viral antibody resistance mechanisms
- Assessment of the impact of resistance-associated mutations on viral fitness
- Establishment and performance of immunological and virological assays, including:
- Primary cell work and cell culture
- Virus cultures
- PCR, cloning, and molecular biology techniques
- Flow cytometry, ELISA, immunohistochemistry
- Analysis of large viral sequence and phenotypic datasets
- Presentation of results at internal meetings and national and international conferences
- Preparation of manuscripts with the goal of publishing in high-impact international journals
Division of Infectious Diseases – Department I of Internal Medicine
We are seeking a highly motivated PhD student (f/m/x) with a strong interest in immunology, virology, and infectious diseases to join our Emmy Noether–funded translational research group. The project focuses on characterizing viral antibody resistance mechanisms in people living with HIV, combining patient-derived data with state-of-the-art experimental and computational approaches.